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Evidence: LowPeptide Research Only Cosmetic & Skin

Myristoyl Hexapeptide-16

also known as: Myr-LKKALK

Myr-LKKALK, a lash-serum lipopeptide often paired with myristoyl pentapeptide-17. No published study of it exists on PubMed.

Myristoyl hexapeptide-16 is a synthetic lipopeptide, a myristoyl group on the hexapeptide Leu-Lys-Lys-Ala-Leu-Lys (PubChem's record gives the structure under its INCI name). It appears in eyelash serums, but a title-and-abstract search of PubMed for its INCI name, matched word by word, finds no study of it. It is not a drug and has no drug approval.

No dosing data yet Details ↓

Dosing

Recommended Dosing

No dosing data yet

This page has no dosing data yet.

Mechanism of action

Not established: no published study describes its action.

Primary uses

Cosmetic eyelash and eyebrow serums

Typical dosing

Not established for human use

No controlled study of the ingredient on its own states an amount used on skin, and a supplier's use level is not a source on this site, so none is given.

Regulatory status

Not a drug: listed as a cosmetic ingredient under its INCI name (PubChem CID 163285863). Drugs@FDA and the EMA medicines list hold no record for it (searched October 28, 2026).

Status as of this entry's last review, October 28, 2026. Approvals, compounding rules and sport rules change; the regulatory tracker is checked more often.

What we checked

Myristoyl hexapeptide-16 is a lash-serum lipopeptide with no published literature; this section records what can be checked.

Identity, computed

Structure	myristoyl-Leu-Lys-Lys-Ala-Leu-Lys, free acid (PubChem's IUPAC name, CID 163285863)
Formula	C47H91N9O8 (PubChem)
Molecular weight	910.3 g/mol (PubChem)

The calculator used elsewhere on this site does not handle a myristoyl cap, so the formula and weight are PubChem's, not computed here.

Regulatory status, read October 28, 2026

Drugs@FDA: 0 records for “myristoyl hexapeptide-16”. EMA medicines list: 0 records for “myristoyl hexapeptide-16”. Run for semaglutide, the same queries return 6 and 5 records (and the registry search 80 trials), so a zero here is an absence, not a broken search. Not named on the WADA 2026 and 2027 Prohibited Lists. As a substance with no current approval for human therapeutic use, it falls under section S0 (non-approved substances), which is prohibited at all times; the lists were read on October 28, 2026.

What we looked for and did not find

No published study of any kind, no registry record and no drug approval.

Source	Query	What it was
PubMed	("hexapeptide-16"[tiab] OR "hexapeptide 16"[tiab]) AND myristoyl[tiab]	the hyphenated INCI name is matched word by word (Q958): a phrase search for a hyphen-numbered name misses papers
ClinicalTrials.gov	myristoyl hexapeptide-16
Drugs@FDA (openFDA)	myristoyl hexapeptide-16
EMA medicines list	myristoyl hexapeptide-16

References

[other] PubChem CID 163285863, Myristoyl Hexapeptide-16: formula C47H91N9O8, molecular weight 910.3. Read October 28, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/163285863

Related peptides

Myristoyl Pentapeptide-17

Myr-KLAKK-NH2, the lipopeptide in many eyelash and brow serums. PubMed holds no study of it, so claims about lash growth rest on marketing, not published data.

Biotinoyl Tripeptide-1

Biotin joined to the tripeptide GHK, sold for hair-loss products inside the blend Procapil. The two trials found tested Procapil alongside platelet-rich plasma.

Acetyl Tetrapeptide-3

Ac-KGHK-NH2, a cosmetic tetrapeptide used in hair-loss lotions. Its only human trial tested it inside a three-ingredient herbal blend, so its own effect on hair is untested.

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Disclaimer

This entry is for educational purposes only and does not constitute medical advice. Dosing information reflects published regulatory or research data and is not a recommendation. Many compounds described here are not approved for human use in the United States. Consult a licensed medical professional before considering any peptide therapy.