Myristoyl Tetrapeptide-12
Myr-KAKA-NH2, a lipopeptide used in lash and brow serums. PubMed holds no study of it.
Myristoyl tetrapeptide-12 is a synthetic lipopeptide, a myristoyl group on the tetrapeptide amide Lys-Ala-Lys-Ala-NH2 (PubChem's record, under its INCI name). It appears in eyelash and eyebrow serums, but a title-and-abstract search of PubMed for its INCI name finds no study of it. It is not a drug.
No dosing data yet Details ↓
Recommended Dosing
No dosing data yet
This page has no dosing data yet.
Mechanism of action
Not established: no published study describes its action.
Primary uses
- Cosmetic eyelash and eyebrow serums
Typical dosing
No published study states an amount of this ingredient used on skin, and a supplier's use level is not a source on this site, so none is given.
Regulatory status
Not a drug: PubChem lists it under its INCI name as a cosmetic ingredient (CID 127264658). Drugs@FDA and the EMA medicines list hold no record for it (searched October 28, 2026).
Status as of this entry's last review, October 28, 2026. Approvals, compounding rules and sport rules change; the regulatory tracker is checked more often.
What we checked
Myristoyl Tetrapeptide-12 is a cosmetic peptide ingredient with little or no published literature; this section records what can be checked.
Identity, computed
| Structure | myristoyl-Lys-Ala-Lys-Ala-NH2 (PubChem's synonym and IUPAC name, CID 127264658) |
| Formula | C32H63N7O5 (PubChem) |
| Molecular weight | 625.9 g/mol (PubChem) |
The calculator used elsewhere on this site does not handle a myristoyl cap, so the formula and weight are PubChem's, not computed here.
Regulatory status, read October 28, 2026
Drugs@FDA: 0 records for “myristoyl tetrapeptide-12”. EMA medicines list: 0 records for “myristoyl tetrapeptide-12”. Run for semaglutide, the same queries return 6 and 5 records (and the registry search 80 trials), so a zero here is an absence, not a broken search. Not named on the WADA 2026 and 2027 Prohibited Lists. As a substance with no current approval for human therapeutic use, it falls under section S0 (non-approved substances), which is prohibited at all times; the lists were read on October 28, 2026.
What the maker or sellers claim
Claim, from cosmetic marketing: the ingredient makes lashes look longer or fuller. No published study of it was found, in people or in the laboratory.
What we looked for and did not find
No published study of any kind, no registry record and no drug approval.
| Source | Query | Results, October 28, 2026 | What it was |
|---|---|---|---|
| PubMed | ("tetrapeptide-12"[tiab] AND myristoyl[tiab]) | 0 | name matched word by word in title/abstract (a phrase search misses hyphen-numbered names) |
| ClinicalTrials.gov | myristoyl tetrapeptide-12 | 0 | |
| Drugs@FDA (openFDA) | myristoyl tetrapeptide-12 | 0 | |
| EMA medicines list | myristoyl tetrapeptide-12 | 0 |
References
- [other] PubChem CID 127264658, Myristoyl Tetrapeptide-12: formula C32H63N7O5, molecular weight 625.9. Read October 28, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/127264658
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This entry is for educational purposes only and does not constitute medical advice. Dosing information reflects published regulatory or research data and is not a recommendation. Many compounds described here are not approved for human use in the United States. Consult a licensed medical professional before considering any peptide therapy.